Automated variant interpretation, built for research review.
For research use only — intended for clinicians reviewing variants in a research setting, not for diagnosis, treatment decisions, or patient care. GeneGenius turns a variant call into an evidence-linked research report — a readable summary plus a detailed evidence view of the same result, so the research signal is understandable fast.
Evidence-linked interpretation, ready to review
Everything below is for research use. It is designed to accelerate comprehension of a genomic result — not to make a diagnosis.
- Automated variant interpretation with ACMG/AMP-aligned classification, led by core signals (e.g. PVS1, PS1, PM2).
- Evidence-grounded, citation-backed research reports you can download as a PDF.
- Pharmacogenomics research signals drawn from PharmGKB and OpenFDA — informational context, not dosing or treatment guidance.
- Phenotype-driven prioritization — HPO terms mapped to the most relevant variants. Validated on synthetic clinical notes; real-world EHR validation in progress.
- Continuous reanalysis — automatic re-flagging when a VUS is reclassified as new evidence lands.
Summary first, evidence on demand
The same result is presented at two levels of detail, so a fast read and a deep review live in one place.
Summary view
A readable top-line view of the result, so the research signal is understandable fast.
Detailed evidence view
The same result expanded into supporting evidence, scores, and classification rationale.
Traceable citations
Every claim links back to its source, so findings can be reviewed and reproduced.
Research Use Only
GeneGenius is for research use only (RUO). It is not a diagnostic device and is not intended for use in diagnosis, treatment decisions, or the prevention of disease. Pharmacogenomic and classification outputs are research signals under ongoing validation.
See GeneGenius on your own data.
From a raw VCF or FASTQ to an interpretable, evidence-linked research report — in minutes.
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